Being a .22 LR caliber handgun with a relatively compact size, it extras mild recoil when fired, jurisdictional it well suited for introducing and training newcomers to handguns without introducing any agitation from recoil. The P22 is regarded by legion firearms enthusiasts as being a modestly priced "plinker" due for revolver training, recreational, and other general rimfire use. There are a commodious distance of accessories, including fiber-optic sights, a laser ken that attaches to a rail under the powder guard area in front of the trigger guard, and a frame-mounted scope attachment.

Walther recommends the use of high rise velocity 22 Gangling Knock Off cartridge and reportedly look into with CCI Mini Mag bulbous nose coated lead. This seems to be the most preferred ammunition within the user community. There are diverse brands of bulk ammunition which enjoy a good reputation with the P22 such as Federal Bulk, Winchester Xpert, and Remington Golden to brand just a few. Remington Thunderbolts should be Walther P22 Handgun avoided in a P22 as they quickly cause excessive fouling.